Wolfsburg lost ground on Bayern Munich at the top of the Bundesliga after being held to a 1-1 draw at home to Schalke on Sunday.
Kevin De Bruyne equalised for the Wolves with 12 minutes left after Leroy Sane had given Schalke the lead shortly after half-time.
The draw leaves the hosts 12 points behind Bayern, who can wrap up their third-straight title by bettering Wolfsburg's result next weekend, while Schalke edged back up to fifth, four points ahead of Werder Bremen in the race for a spot in the Europa League next season.
Bruno Labbadia's first game in his second spell as Hamburg coach ended in a 1-0 defeat as they went down to a late Franco Di Santo penalty in the northern Germany derby at Werder Bremen.
Di Santo struck in the last five minutes of a tense and combative derby after Valon Behrami was sent off after hauling down Zlatko Junuzovic to concede the spot-kick.
Defeat leaves bottom side Hamburg four points below 15th-placed Hannover who occupy the final position of definite safety, while Bremen's first win in five games moves them up to seventh.
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Kane, 21, became the first Spurs player to reach the landmark since former striker Gary Lineker in 1991-92 after scoring in the 3-1 win over Newcastle.
Pochettino said: "Congratulations to him because he deserves this moment.
"I think he needs to pay for a dinner this week for his team-mates. The team work a lot and try to help him score."
Asked if Lineker's record was playing on his mind, Kane told BBC Sport: "Not really. After I got to 20 goals, I set myself a target of 30 and it felt like I was on 29 for ages.
"But now I've got here I'm delighted. Maybe I need to set myself another target from now to the end of the season [but] I will keep that quiet.
"It was a special occasion and to get the win makes it even more special."
Victory over Newcastle lifted Spurs above Southampton into sixth, level on points with fifth-placed Liverpool and seven points behind fourth-placed Manchester City.
Pochettino takes his side back to former club Southampton next Saturday and although his side are on course to qualify for next season's Europa League, the Argentine admitted that achieving a top four place would be "very difficult".
"It's not easy after the victory for Manchester City [over West Ham] ," he said. "But we need to always put in a challenge in the next game and try to improve our performance and to be stronger every day. Realistically it's very difficult but we need to try to get the points."
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